Best CBD Oil For Pain Relief Of 2025: 3 Brands To Reduce Aches

CBDPure Full Spectrum CBD Oil

CBDPure Full Spectrum CBD Oil

CBDPure Hemp Oil 1000 has been developed for those looking for a ultra-high dose of CBD in a tincture. Each daily serving of CBDPure Hemp Oil 1000 delivers 33 mg of cannabidiol via a natural and organically grown hemp oil.

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FABCBD Full Spectrum CBD Oil

FABCBD Full Spectrum CBD Oil

FABCBD Oil is crafted from the finest organic industrial hemp plants while keeping the naturally occurring terpenes and other beneficial cannabinoids in place. FAB CBD highest quality oils are designed as high accessibility, full-spectrum blends that contain less than the required legal limit of 0.3% THC from hemp.

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cbdMD Full Spectrum CBD Oil

cbdMD Full Spectrum CBD Oil

CBD oil tinctures provide the simplest, purest, and most versatile way to take your daily CBD. Made with Superior Broad Spectrum CBD formula infused in MCT oil, cbdMD tinctures come in a wide range of concentrations without any THC.

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An estimated 50 million adults in the United States (U.S.) are affected by chronic pain. Not only is chronic pain linked to anxiety, depression, and reduced quality of life, but it’s also associated with opioid dependence.

Cannabinoids — especially cannabidiol (CBD) — are often proposed as opioid alternatives, having comparable effectiveness as well as a better safety profile. But with all the different CBD oils available, narrowing down your choices can be difficult.

This article explains how CBD oil may help people with chronic pain (like back pain and arthritis pain) and reviews the best CBD oil for pain.

3 Best CBD Oils For Pain Management On The Market In (February 2025)

How Can CBD Reduce Pain?

The human body contains a cell-signaling system called the endocannabinoid system, or ECS. The ECS regulates several functions throughout the body, including pain sensation, sleep, appetite, and immune system response.

It is believed that taking CBD oil can help reduce chronic pain by reducing inflammation, interacting with neurotransmitters in your central nervous system, and affecting endocannabinoid receptor activity.

One 2019 study examined the impact of full-spectrum CBD extract on opioid use and quality of life indicators among 97 chronic pain patients for eight weeks.

Researchers found that 53% of participants could reduce or eliminate opioids within eight weeks after adding CBD-rich hemp extract to their regimens, and 94% reported improvements in quality of life. Notably, most participants consumed around 30 milligrams (mg) of CBD daily, divided into two doses.

Best CBD Oils For Pain Management In 2025

CBDPure Hemp Oil 1000mg

CBDPure Hemp Oil 1000mg

If you’re looking for high-quality CBD oil at an affordable price, CBDPure Hemp Oil 1000mg is a good option.

  • Contains 33 mg of cannabidiol per daily serving
  • Each bottle contains 1000 mg of CBD & less than 0.3% THC by weight
  • Natural and organically grown hemp oil
  • Natural hemp flavor
  • Backed by a 90 day Money Back Guarantee
One-Time Purchase $79.99

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CBDPure is a grower and producer of high-quality full-spectrum CBD oil derived from organically grown industrial hemp from Colorado and Washington.

CBDPure Hemp Oil 1000 comes in a natural hemp flavor and contains 1000mg of CBD per bottle, in addition to all the cannabinoids, terpenes, and nutrients in organic hemp. In each 1mL serving, you’ll get 16.6mg of CBD.

All products sold by CBDPure are tested by a third party for cannabinoid profiling, microbial contamination, pesticides, and solvents. Lab results are publicly available online for all products.

Pros & Cons Of CBD For Pain

CBD is considered safe and well-tolerated by most individuals. It’s also easy to use, doesn’t require a prescription, and has several clinical trials to support its effectiveness at relieving pain, sometimes enabling individuals to cut down on or discontinue their opioid pain medication.

However, there are a few possible side effects and other cons associated with CBD use.

According to a 2017 review, the most commonly reported side effects of CBD include:

  • Diarrhea
  • Fatigue
  • Changes in appetite and weight

Additionally, CBD has the potential to interact with some over-the-counter dietary supplements such as St. John’s Wort. It also may interact with certain prescription medications, such as those accompanied by a grapefruit warning. CBD use in pregnant women, breastfeeding women, and children is also not recommended.

Though some evidence suggests CBD may have modest pain-relieving benefits, it’s essential to keep in mind that it has not been approved by the Food and Drug Administration (FDA) to treat pain.

How To Take CBD Oil For Pain Relief & Dosage

Since the FDA has not approved CBD products for pain relief treatment, there are no established clinical guidelines for their dosage.

The amount of CBD you should take will depend on your body weight, body chemistry, and the severity of your pain.

The Arthritis Foundation suggests starting with a few milligrams of CBD oil in sublingual form (applied under the tongue) twice daily. If you do not experience relief after one week, increase your dose by that same amount. Remember that putting the oil under your tongue to be absorbed into the bloodstream is a quicker route to achieving desired effects than putting the drops in juice or a beverage and being digested by the gastrointestinal tract.

Continue to increase your dose until you find relief gradually. Once you find your optimal CBD dose, take it regularly to ensure it remains in your bloodstream. Studies  [20] suggest chronic use and doses up to 1,500 mg have been well-tolerated, but every person is different.

How We Choose The Best CBD Oils For Pain

When choosing the best CBD oils for pain, there are several key factors we took into consideration.

Brand Transparency

We looked at each brand, its manufacturing process, customer reviews, and whether the company has been subject to an FDA warning letter.

We also looked at whether the company utilizes third-party testing and if they provide proof by sharing COAs on their website.

All products reviewed have gone through rigorous tests for pesticides, heavy metals, and molds and contain less than 0.3% THC — the threshold included in the United States hemp laws.

Ingredients

Since you are consuming CBD oils, ingredients are important. We suggest choosing CBD oils made as naturally as possible from hemp grown organically in the United States to reduce the risk of negative health implications. Avoid products made with artificial ingredients, unnecessary fillers, and additives.

Extraction Method

You can extract CBD from hemp using various solvents, including ethanol, methanol, hexane, butane, or ether. However, these extraction methods can leave behind harmful chemical residues.

CO2 extraction is considered a clean way to extract CBD from hemp and tends to produce a superior product.

Final Thought

Some evidence suggests that CBD may help reduce pain, but more research is required. If you are considering using CBD oil for pain, choosing products that have undergone third-party testing is vital.

You’ll also want to speak with your healthcare provider before incorporating CBD into your treatment plan.

Frequently Asked Questions

Does CBD oil work for joint pain?

Several studies suggest that CBD may help alleviate joint pain and muscle pain, but more research is needed.

Is CBD oil or cream better for pain?

CBD capsules or oils are generally recommended over creams to treat pain. Whether creams can deliver CBD below the skin is unknown. However, a recent 2020 study showed relief of neuropathic pain using a CBD cream in patients with peripheral neuropathy, indicating that the cream did penetrate the skin’s barrier to provide pain relief.

How long does it take for CBD oil to kick in?

The effects of CBD oil can usually be felt within 15-45 minutes, depending on whether it is taken so that it is absorbed directly into the bloodstream or has to pass through the gastrointestinal tract.

How do I use CBD oil for pain? How much should I take?

While there are no official CBD dosing guidelines, experts suggest starting with a small dose of just a few milligrams. You can gradually increase your dose each week until relief is felt.

What is the best CBD strain for pain?

Any of the strains mentioned above are a good starting place to find out what CBD strain is best to relieve your pain. The studies done on CBD and pain have primarily used full-spectrum products.

What is the best CBD oil for peripheral neuropathy pain?

Full-spectrum CBD oil is the best for peripheral neuropathy pain because it contains all of the natural compounds in hemp, including terpenes, trace cannabinoids, and flavonoids. These compounds work together to boost the effectiveness, producing the “entourage effect”.