CBDPure CBD Topical Cream
CBDPure Muscle & Joint 500 is a next-generation topical CBD cream specially formulated for rapid absorption. Developed for people with active lifestyles, it combines the power of CBD with trusted botanicals like menthol and white willow bark (aka nature’s aspirin) to provide comfort where you need it most.
CBDfx Cream For Muscle & Joint
CBDfx Muscle and Joint Cream is designed to soothe everyday aches and pains in your deep tissue and joints. In addition to organic broad spectrum CBD, this powerful cream contains several effective ingredients, including cooling menthol and natural pain relievers, white willow bark and caffeine.
As you get older, your body may not work as well as it used to. Everyday activities leave you feeling sore and pain is more likely to become part of your daily life. According to the CDC, over 20% of American adults experience chronic pain, and for more than 36% of those who reported chronic pain, it has a high impact on their daily life. Let’s find out the best CBD cream for pain available on the market in 2025.
Mild or occasional pain can generally be managed with over-the-counter pain relievers or anti-inflammatories, but if you suffer from pain daily you may be looking for an alternate solution. That’s where CBD products come in.
Best CBD Pain Relief Creams On The Market In February 2025
CBD Cream For Pain
Though the Food and Drug Administration (FDA) only changed regulations on CBD to declassify it as a controlled substance in 2018, medically reviewed research on the benefits of CBD is still limited. That being, cannabinoids like CBD and THC have been studied for their potential anticonvulsant, anti-inflammatory, and analgesic benefits.
Evidence for this, especially in specific populations such as older subjects and cancer patients is still in the works but shows promise. If you experience chronic pain, CBD pain cream could help. Rather than ingesting cannabidiol along with a carrier oil, you apply the product directly to the site of your pain to experience faster relief and specifically to the applied area.
In this article, we’ll explore the subject of CBD for pain relief, particularly in its topical form. You’ll also see our top 10 picks for the best CBD creams for pain.
Best CBD Creams For Pain In 2025
CBDPure CBD Muscle & Joint Cream
If you’re suffering from joint and muscle pain, CBD Pure has the best CBD cream for arthritis pain. Their Muscle & Joint formula contains 500mg of full-spectrum CBD and other anti-inflammatory ingredients.
- Contains 500 mg of full-spectrum CBD
- Menthol and White Willow Bark boosts its effectiveness
- Non-greasy formula
- Backed by a 90 day Money-Back Guarantee
Why suffer from chronic joint issues when CBD creams may help? CBD Pure keeps it simple with their Muscle & Joint formula which contains 500 mg of CBD per 3-ounce tube. This formula is supplemented with cooling menthol and anti-inflammatory white willow bark extract along with other premium-quality ingredients. Plus, you get a 90-day satisfaction guarantee.
How Does CBD Cream Work For Pain?
Cannabidiol is one of over 100 cannabinoid compounds found in the cannabis plant. There are several varieties of cannabis, but CBD is most highly concentrated in hemp (Cannabis sativa). Its cousin, tetrahydrocannabinol (THC), is more highly concentrated in marijuana (Cannabis indica). Both of these compounds are thought to work by impacting the endocannabinoid system (ECS) present in the bodies of all mammals.
Cannabinoids bind to or modulate the ECS’ primary receptors (CB1 and CB2) and, in doing so, help modify or regulate certain bodily processes such as inflammation or the expression of pain. Though cannabidiol is typically ingested, it can also be absorbed through the skin to provide more direct relief. That is how CBD cream is thought to work to relieve pain.
Medical research supports the benefits of CBD for pain, but many studies involve treatment with ingested or inhaled cannabidiol products rather than topicals. Anecdotal evidence shows the potential of CBD topicals to relieve pain, but it is unclear how much of the benefit can be attributed to the cannabidiol and how much to other ingredients in the product.
What Is The Best CBD Cream For Pain?
When it comes to the best CBD creams, it’s largely a matter of opinion. Cannabidiol products affect everyone differently, so you may need to work with your doctor to find a CBD pain cream with the right concentration of cannabidiol to address your symptoms. For people using CBD for the first time, you may want to start with a low concentration for a few weeks to see how the body reacts. If you’re not seeing the desired results, increase your dose slowly as needed.
In terms of shopping for CBD topicals, it’s important to choose a company that uses a high-quality source of cannabidiol and other ingredients from nature. Make sure the products you’re considering are tested by a third-party lab for purity and potency – see if you can find a COA online to verify. It also doesn’t hurt if the company offers a money-back guarantee just in case you’re not satisfied with the product.
Do CBD Topicals Have Side Effects?
Generally speaking, CBD is highly regarded as safe. In a medically reviewed 2018 publication, the World Health Organization (WHO) describes CBD as, “generally well tolerated with a good safety profile.” They also comment that adverse effects are likely the result of an interaction between CBD and medications the patient is already taking.
That being said, it’s always a good idea to be aware of the possibility of side effects. With CBD, side effects are typically mild and usually limited to drowsiness, diarrhea, and changes in weight or appetite. Keep in mind, however, that these side effects typically refer to ingested products. With a topical product like a CBD salve or cream, negative reactions may be caused by other ingredients in the product such as artificial fragrance or synthetic additives.
Final Thoughts
More research is needed to determine the benefits of topical CBD, but the analgesic properties of cannabidiol are the best supported. People who suffer from pain may experience relief when using CBD creams or salve, though it may depend on the concentration of the product. Talk to your doctor about the recommended dosage for the severity of your symptoms then try out a cream for a few weeks to see how it works. You may need to increase the dose to experience the desired effect.
Frequently Asked Questions
Are CBD products legal?
Yes. As of 2018, the Food and Drug Administration (FDA) no longer regards CBD as a controlled substance. It is legal as long as it contains less than 0.3% THC by dry weight.
Is CBD oil or CBD cream better for pain?
It depends. Ingesting CBD oil may help reduce inflammation and manage chronic pain when used daily but CBD pain cream may help people with flare-ups and severe symptoms.
How much CBD do I need?
There is no standard dosage for CBD, so the amount you need may depend on the condition you’re treating and the severity of your symptoms. The best CBD creams come in a range of concentrations, so talk to your doctor for recommendations.